Kumari Palany & Co

Tamilnadu leading in altruistic cadaver liver donation

Posted on: 31/May/2010 1:03:56 AM

K.Ravindranath, chairman, Global Hospitals and  Mohamed Rela, Liver Transplant specialist, were addressing  a press conference Chennai on Sunday.

They said that liver transplantation scene in India has improved to the extent that it is comparable with world standards.  Mohamed Reja is a pioneer in liver transplantation pioneer Mohamed Reja.

He said that good liver transplants were able to provide a one-year survival in 90 per cent of cases (75 per cent of cases with acute liver failure), a five-year survival rate for 85 per cent of patients and a 10-year survival rate in about 70 per cent of cases.

Apart from medical expertise and technological advances, the enormous changes in the transplantation scenario were also due to the raised awareness leading to more cadaver and living donor transplants, Dr. Rela said. Tamil Nadu, especially Chennai, was the forerunner for altruistic cadaver liver donation, and the mobilization of the organized sector of the government was now a model for other States, he said.

“In terms of long-term survival of ten years or longer, results with liver transplantation are better than that with renal transplants,” Dr. Rela said.

While liver transplants now cost about Rs.22 lakh for adults and half that amount for children, the usage of immunosuppressants could be tapered down, leading to lesser post-transplant costs, he said.

Pointing to liver cancers as among the most common causes of liver disease, Dr. Rela said the lack of screening was leading to patients presenting with fairly advanced cancers.

Later, addressing a scientific session, Dr. Rela said transplants could be offered for benign liver tumours, which if left unattended could be lethal through “mass effect than metastasis.”

In a condition like hepatoblastoma - an important liver tumor in children — the worldwide experience has been that any tumor that does well with chemotherapy did well with resection. However, pre-operative chemotherapy is an important intervention prior to resesection procedure.

On hepatocellular carcinoma, which was one of the most common cancers, Dr. Rela said it was important to appreciate the condition as two diseases rolled into one with both having different prognosis.

While resection, chemo-embolisation, radio frequency ablation and liver transplantation were among the available options to treat liver cancers, one of the problems in India was that each centre offered different treatment modality that they had, Dr. Rela said.